Team leader

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    Norma Carmen Gutiérrez Gutiérrez

    Complejo Asistencial Universitario de Salamanca

Research team:
  • Patricia Blázquez Benito
  • Luis Antonio Corchete Sánchez
  • Cristina de Ramón Sánchez
  • Manuel Delgado Criado
  • Yolanda Dosantos Vara
  • Patryk Krzeminski
  • María Victoria Mateos Manteca
  • Irene Misiewicz Krzeminska
  • Dalia Quwaider
  • Irene Real Ibáñez
  • Elizabeta de los Ángeles Rojas Ricardo
  • Pilar Amalia Paz Rodríguez
  • Gloria Pérez Martín
Technical associates:
  • Dolores Corrales Sierra
  • María CortésRodríguez
  • Vanesa Gutiérrez Moreta
  • Sara Marcos Corrales
  • Mª Teresa Prieto Martín
  • Laura San Segundo Payo
Research associates:
  • Ignacio Jesús Cardona Benavides
Support staff:
  • Mónica Sánchez Sánchez
Support staff associates:
  • Isabel María Isidro Hernández

Research focus:

  • Identify factors that condition the malignant transformation of monoclonal gammopathy of undetermined significance and quiescent myeloma in active myeloma.
  • Reveal within the phenotypic and functional heterogeneity of the tumour cell of multiple myeloma prognostic markers associated with a short survival time, in order to design effective therapeutic strategies adapted to the patient -personalised medicine.
  • Observe the phenotypic characterization of the tumour cell of highly resistant multiple myeloma, persisting after treatment in small groups (minimal residual disease) and responsible for the patients' relapse -myeloma stem cells.
  • Identify the mechanisms responsible for drug-resistance in myeloma tumour cells, persisting after treatment.
  • Evaluate potential therapeutic targets based on the study of the pathogenesis of the disease and research into drug combinations aimed towards these mechanisms that result in a synergistic antitumour effect.


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