Team leader
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José Juan García Marín
Universidad de Salamanca
Research team:
- Maitane Asensio Martín
- Óscar Briz Sánchez
- Candela Cives Losada
- Kevin Delgado Calvo
- Álvaro Gacho Temprano
- Elisa Herráez Aguilar
- Nazaret Hortelano Hernández
- Silvia Jiménez Cabrera
- Elisa Lozano Esteban
- María Jesús Monte Río
- Sara Ortiz Rivero
- María Reviejo Díaz
- Rocío Rodríguez Macías
- Marta Rodríguez Romero
- Beatriz Sánchez de Blas
- Anabel Sánchez Martín
- Paula Sanchón Sánchez
- Mª Ángeles Serrano García
Research associates:
- ---
Research focus:
- Development of gene and cell therapy strategies aimed at increasing the response to available antitumour drugs for liver tumours and colon cancer.
- Study the function and adjustment of the expression of the ABC superfamily proteins and their implications in liver physiology, pathophysiology and pharmacology.
- Role of SOS genes against the chemical aggression in the mechanisms involved in the lack of response to medicinal treatment in liver tumours and colon cancer. Finding and evaluating chemoresistance predictive tools.
- Research the relationship between nuclear (FXR and SHP) and membrane (TGR5 and FDGFR4) receptors with regeneration, carcinogenesis and chemoresistance in enterohepatic tissues.
- Synthesis and evaluation of new drugs with vectorial characteristics based on the capacity of the SLC superfamily to introduce them in cells in order to boost their intracellular concentration in tissues of the enterohepatic axis that express them.
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