Features
The work program for Cluster 1 (Health) under Horizon Europe has been published: Work Program Horizon Europe Cluster 1 Health 2025. It is part of the new Horizon Europe strategic plan for the 2025–2027 period. The main priorities focus on social cohesion, inclusion, and the overall health and well-being of Europeans, in line with the European Pillar of Social Rights. Other key priorities include the need to modernize health care systems and to support an innovative, sustainable, and competitive health industry in Europe.
More specifically, Cluster 1 strives to contribute to six expected impacts as set forth in the Strategic Plan, which are distributed across the following topics:
HORIZON-HLTH-2025-03-STAYHLTH-01-two-stage: Improving the quality of life of people with intellectual disabilities and their families
HORIZON-HLTH-2025-03-ENVHLTH-01-two-stage: The Impact of Pollution on the Development and Progression of Brain Diseases and Disorders
HORIZON-HLTH-2025-03-ENVHLTH-02-two-stage: Advancing knowledge on the impacts of micro- and nanoplastics on human health
HORIZON-HLTH-2025-01-DISEASE-01: Testing the safety and efficacy of phage therapy for the treatment of antibiotic-resistant bacterial infections
HORIZON-HLTH-2025-03-DISEASE-02-two-stage: Advancing Innovative Interventions for Mental, Behavioral, and Neurodevelopmental Disorders
HORIZON-HLTH-2025-01-DISEASE-03: Development of antibodies and antibody-derived proteins for the prevention and treatment of infectious diseases with epidemic potential
HORIZON-HLTH-2025-01-DISEASE-04: Leveraging Artificial Intelligence for Pandemic Preparedness and Response
HORIZON-HLTH-2025-01-DISEASE-05: Support for the operations of the Global Research Collaboration for Infectious Disease Preparedness (GloPID-R)
HORIZON-HLTH-2025-01-DISEASE-06: Implementation research addressing strategies to strengthen health systems for equitable, high-quality care and health outcomes in the context of noncommunicable diseases (GACD)
HORIZON-HLTH-2025-01-DISEASE-07: Addressing the high burden on patients and under-researched medical conditions
HORIZON-HLTH-2025-02-DISEASE-01: European Partnership for Brain Health
HORIZON-HLTH-2025-02-DISEASE-02: European partnership to foster a European Research Area (ERA) for health research (Phase 2)
HORIZON-HLTH-2025-01-CARE-01: End-user-driven application of generative artificial intelligence models in healthcare (GenAI4EU)
HORIZON-HLTH-2025-01-TOOL-01: Enhancing Cell Therapies with Genomic Techniques
HORIZON-HLTH-2025-01-TOOL-02: Advancing Cell Secretome-Based Therapies
HORIZON-HLTH-2025-01-TOOL-03: Leveraging Multimodal Data to Advance the Applicability of Generative Artificial Intelligence in Biomedical Research (GenAI4EU)
HORIZON-HLTH-2025-01-TOOL-05: Accelerating the translation of biotech research into innovative health therapies
HORIZON-HLTH-2025-01-IND-01: Optimizing the Manufacturing of Advanced Therapy Medicinal Products (ATMPs)
HORIZON-HLTH-2025-01-IND-02: Digitalization of Conformity Assessment Procedures for Medical Devices and In Vitro Diagnostic Medical Devices
HORIZON-HLTH-2025-03-IND-03-two-stage: Facilitating the conduct of multinational clinical studies of orphan devices and/or highly innovative (“breakthrough”) devices
**If you’re interested in any of our opportunities or need more information, please don’t hesitate to contact us, and we’ll send you the relevant information sheet.**
Requirements:
These calls for proposals are aimed at multidisciplinary European consortia. Unless otherwise specified in the specific conditions of the call, only legal entities that form a consortium will be eligible to participate in the actions, provided that the consortium includes, as beneficiaries, three legal entities that are independent of one another, each established in a different country, in accordance with the following criteria:
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at least one independent legal entity established in a Member State; and
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at least two other independent legal entities, each established in different Member States or Associated Countries.
Legal entities established in Russia, Belarus, or in territories of Ukraine not controlled by the government are not eligible.
How to apply
Applications consist of two sections:
-Part A (to be completed online) contains administrative information related to the consortium, the budget, and specific details of the call for proposals.
-Part B (a template downloaded from the Commission’s website must be completed) contains the scientific and technical aspects of the project.
Submission deadline.
If the application process consists of two phases, these are the dates:
-Single stage: September 16, 2025
-Two stages: April 16, 2026
If the calls for applications are for a single phase, the deadline is:
-Single stage: September 16, 2025