Clinical Practice Guidelines
Clinical practice guidelines (CPGs) are documents that contain a set of systematically developed recommendations, designed to help both clinical staff and patients make decisions about the most appropriate interventions for addressing a health problem in specific circumstances.
List of Clinical Practice Guidelines for IBSAL Professionals
2025
Title: Recommendations for the Study of Monoclonal Gammopathies in the Clinical Laboratory. A Consensus of the Spanish Society of Laboratory Medicine and the Spanish Society of Hematology and Hemotherapy. Part III: Clinical and Analytical Recommendations for the Study of Monoclonal Gammopathies by MALDI-TOF Mass Spectrometry
IBSAL Authors: Cristina Agulló, Noemí Puig, and María Victoria Mateos
Publication date: November 4, 2025
Journal: Clinical Chemistry and Laboratory Medicine (CCLM)
Title: SEOM-GEMCAD-TTD Clinical Guidelines for Localized Rectal Cancer (2025)
IBSAL Authors: Rosario Vidal-Tocino
Publication date: December 3, 2025
Journal: Clinical and Translational Oncology
Title: International Myeloma Society/International Myeloma Working Group Consensus Recommendations on the Definition of High-Risk Multiple Myeloma
IBSAL Authors: María Victoria Mateos
Publication date: June 9, 2025
Journal: Journal of Clinical Oncology
Title: Consensus Document on COVID-19 from the Spanish Society of Primary Care Physicians (SEMERGEN). Current Situation. SEMERGEN’s Position in 2025
IBSAL Authors: Elena Navarro Matías
Publication date: July–August 2025
Journal: Family Medicine. SEMERGEN
Title: Common Catalog of Genetic and Genomic Tests of the Spanish National Health System (SNS)
IBSAL Authors: IIMD-01 – Allergy
Website: Ministry of Health. Government of Spain
Title: Breastfeeding Guide: The Natural Way
IBSAL Authors: Laura San Feliciano Martín
Institutional coordination: Department of Health of the Regional Government of Castile and León, General Directorate of Public Health.
Title: Clinical Protocol for the Use of Axicabtagene Ciloleucel in the Treatment of Adult Patients with Refractory or Relapsed Follicular Lymphoma After Three or More Lines of Systemic Therapy in the National Health System
IBSAL Authors: Alejandro Martín García-Sancho, Fermín Sánchez-Guijo
Publication date: March 3, 2025
Institutional Coordination: Deputy Directorate General of Pharmacy. Directorate General of the National Health System’s Common Service Portfolio and Pharmacy. Ministry of Health
Title: Clinical Protocol for the Use of Brexucabtagene Autoleucel in the Treatment of Patients with Refractory or Relapsed Mantle Cell Lymphoma After Two or More Lines of Systemic Therapy in the National Health System
IBSAL Authors: Alejandro Martín García-Sancho, Fermín Sánchez-Guijo
Publication date: March 3, 2025
Institutional Coordination: Deputy Directorate General of Pharmacy. Directorate General of the National Health System’s Common Service Portfolio and Pharmacy. Ministry of Health
Title: Process for the Prevention and Management of Suicidal Behavior
IBSAL Authors: Ángel Luis Montejo
Institutional Coordination: General Directorate of Health Care; Regional Health Administration; Department of Health of the Regional Government of Castile and León
Title: EHA–EMN Evidence-Based Guidelines for the Diagnosis, Treatment, and Follow-up of Patients with Multiple Myeloma
IBSAL Authors: María-Victoria Mateos
Publication date: July 7, 2025
Journal: Nature Reviews Clinical Oncology
Title: Guide to Multiple Myeloma. Spanish Myeloma Group. 2nd edition
IBSAL Authors: María Victoria Mateos Manteca, Verónica González de la Calle, Norma Gutiérrez Gutiérrez, Noemi Puig Morón
Published by: PETHEMA Foundation
Title: Recommendations for Performing Spirometry
IBSAL Authors: Miguel Ángel Hernández Mezquita
Publication date: January 9, 2026
Journal: Archives of Bronchopneumology
Title: Hematology Guidelines for the Management of Patients with Multiple Myeloma in Castile and León (Version 5.2)
IBSAL Authors: Verónica González de la Calle, Norma Gutiérrez Gutiérrez, NoemÍ Puig Morrón
Publication date: July 30, 2024
Published by: Castile and León Society of Hematology and Hemotherapy
Title: Guidelines for the Management of Philadelphia-Negative Chronic Myeloproliferative Neoplasms
IBSAL Authors: Jesús Mª Hernández Rivas
Publication date: June 4, 2025
Published by: Spanish Group on Philadelphia-Negative Myeloproliferative Disorders (GEMFIN) and the Spanish Society of Hematology and Hemotherapy (SEHH).
Title: Guidelines for the Use of Bispecific Antibodies in B-Cell Non-Hodgkin Lymphomas
IBSAL Authors: Alejandro Martín García-Sancho
Publication date: January 21, 2025
Published by: Spanish Group on Lymphomas and Autologous Bone Marrow Transplantation (GELTAMO)
Title: Guidelines for the Diagnosis, Treatment, and Follow-up of Waldenström’s Lymphoplasmacytic Lymphoma/Macroglobulinemia and Related Conditions
IBSAL Authors: Cristina Jiménez Sánchez
Publication date: December 15, 2025
Published by: Spanish Group on Lymphomas and Autologous Bone Marrow Transplantation (GELTAMO)
Title: Pharmacoclinical Protocol for the Use of Tisagenlecleucel and Axicabtagene Cileucel in Diffuse Large B-Cell Lymphoma in the National Health System
IBSAL Authors: Alejandro Martín García-Sancho, Fermín Sánchez-Guijo
Publication date: April 11, 2025
Institutional Coordination: Deputy Directorate General of Pharmacy. Directorate General of the National Health System’s Common Portfolio of Services and Pharmacy. Ministry of Health
Title: Results of the Study on the Implementation of Safe Practices in the Use of High-Risk Medications in Spanish Hospitals
IBSAL Authors: María José Otero, María Rita Martín Muñoz, Judit García Aparicio
Publication date: December 2025
Published by: Ministry of Health, Institute for the Safe Use of Medicines
Title: 2025 Updated Version v1.0: SEOM-GEMCAD-TTD Clinical Guidelines for the Systemic Treatment of Metastatic Colorectal Cancer (2022)
IBSAL Authors: Ana Fernández Montes, Rosario Vidal Tocino
Publication date: February 25, 2025
Journal: Clinical and Translational Oncology
Title: Recommendations for the Management of Cutaneous Squamous Cell Carcinoma: A Systematic Multidisciplinary Delphi Consensus Approach
IBSAL Authors: Javier Cañueto
Publication date: July 2025
Journal: Clinical and Translational Oncology
Title: European Myeloma Network Group Review and Consensus Statement on Primary Plasma Cell Leukemia
IBSAL Authors: María Victoria Mateos Manteca
Publication date: February 6, 2025
Journal: Annals of Oncology
Title: Recommendations for the Safe Use of High-Risk Medications in Pediatrics
IBSAL Authors: María José Otero
Publication date: July 2025
Journal: Annals of Pediatrics
Title: SEOM-GEICO Clinical Guidelines on Endometrial Cancer (2025)
IBSAL Authors: Teresa Martin Gómez
Publication date: September 23, 2025
Journal: Clinical and Translational Oncology
Title: Catheter-Directed Interventions in Acute Pulmonary Embolism. Position Statement of the SEC-Interventional Cardiology Association/SEC-Ischemic Heart Disease and Acute Cardiovascular Care Association/SEC-Working Group on Pulmonary Hypertension
IBSAL Authors: Javier Martín Moreiras
Publication date: September 23, 2025
Journal: Spanish Journal of Cardiology
Title: Manual for the Diagnosis and Clinical Management of Germline Predisposition to Hematologic Neoplasms
IBSAL Authors: Jesús María Hernández Rivas, José María Bastida Bermejo, María Díez Campelo, Teresa González Martínez, María del Carmen Chillón Santos, Nerea Vidaña Bedera, Mónica del Rey González
Publication date: July 10, 2025
Published by: Spanish Society of Hematology and Hemotherapy
Title: Guide to the Diagnosis and Treatment of Congenital Platelet Disorders
IBSAL Authors: José M.ª Bastida Bermejo, José Ramón González-Porras
Publication date: December 11, 2025
Published by: Spanish Society of Hematology and Hemotherapy
Title: Practical Guidance on the Clinical Management of Belantamab Mafodotin-Associated Ocular Events
IBSAL Authors: María-Victoria Mateos Manteca
Publication date: July 28, 2025
Journal: American Journal of Hematology
Title: Optimizing T-cell Immunotherapy in Patients with Multiple Myeloma: Practical Considerations from the European Myeloma Network
Authors: Maria-Victoria Mateos Manteca
Publication date: June 25, 2025
Journal: The Lancet Haematology
Title: Occupational Exposure to Ionizing Radiation Among Pregnant Workers. Consensus Document by ACI-SEC/ARC-SEC/SERVEI/SENR/SERAM/GeNI
IBSAL Authors:
Publication date: December 2025
Journal: Revista Española de Cardiología: Interventional Cardiology
2024
Title: SEOM-GETNE-TTCC Clinical Guideline on Thyroid Cancer (2023)
IBSAL Authors: Miguel Navarro
Publication date: September 26, 2024
Journal: Clinical and Translational Oncology
Title: Guidelines for the Early Identification and Referral of Patients with B-Cell Non-Hodgkin Lymphoma Who Are Candidates for CAR-T Therapies, Guidelines for the Early Identification and Referral of Patients with B-Cell Non-Hodgkin Lymphoma Who Are Candidates for CAR-T Therapies
IBSAL Authors: Alejandro Martín García-Sancho, María Victoria Mateos Manteca
Publication date: July 12, 2024
Published by: Spanish Society
of Hematology and Hemotherapy
Title: Guide to Conditioning for Hematopoietic Progenitor Cell Transplantation
IBSAL Authors: Estefanía Pérez, Lucía López Corral, Mónica Baile
Publication date: 2024
Published by: Spanish Group for Hematopoietic Transplantation and Cell Therapy (GETH-TC)
Title: Inflammatory and Infectious Aneurysms. Clinical Guidelines from the Castile and León Society of Angiology and Vascular Surgery
IBSAL Authors: Oliver Bonnelly, José Antonio Carnicero Martínez
Publication date: June 20, 2024
Published by: Castile and León Society of Angiology and Vascular Surgery
Title: Update on Infection and Antibiotic Therapy in Angiology and Vascular Surgery. Clinical Guidelines from the Castile and León Society of Angiology and Vascular Surgery
IBSAL Authors: Oliver Bonnelly, José Antonio Carnicero Martínez, José Ángel Torres Hernández, Sergio Valverde García
Publication date: June 20, 2024
Published by: Castile and León Society of Angiology and Vascular Surgery
Title: Clinical Practice Guidelines for the Diagnosis and Treatment of T/NK-Cell Lymphomas 2024
IBSAL Authors: Alejandro Martín García-Sancho
Publication date: October 30, 2024
Published by: Spanish Group on Lymphomas and Autologous Bone Marrow Transplantation and the Spanish Society of Hematology and Hemotherapy
Title: Recommendations for the Management of Cutaneous Squamous Cell Carcinoma: A Systematic Multidisciplinary Delphi Consensus Approach
IBSAL Authors: Javier Cañueto
Publication date: December 19, 2024
Journal: Clinical and Translational Oncology
Title: Use of Multi-Gene Panels in Patients at High Risk for Hereditary Digestive Cancer: Position Statement of AEG, SEOM, AEGH, and the IMPaCT-GENÓMICA Consortium
IBSAL Authors: Rosario Vidal Tocino
Publication date: March 2024
Journal: Gastroenterology and Hepatology
Title: Diagnosis and Treatment of Patients with ANOCA. Consensus Document of the SEC-Clinical Cardiology Association/SEC-Interventional Cardiology Association/SEC-Ischemic Heart Disease and Acute Cardiac Care Association/SEC-Cardiovascular Imaging Association
IBSAL Authors: Ignacio Cruz González
Publication date: September 25, 2024
Journal: Gastroenterology and Hepatology
Title: Recommendations on High-Throughput Sequencing Studies of Hematologic Neoplasms
IBSAL Authors: Carmen Chillón Santos
Publication date: March 21, 2024
Published by: Molecular Biology in Hematology Group (GBMH), Spanish Foundation for Hematology and Hemotherapy (FEHH) – Spanish Society of Hematology and Hemotherapy (SEHH)
Title: Myeloma Blood Test Guide
IBSAL Authors: Verónica González de la Calle
Publication date: July 30, 2024
Published by: Castile and León Society of Hematology and Hemotherapy
Title: Hemophilia Care Guide for Castile and León
IBSAL Authors: José Ramón González Porras, Pablo García Jaén, José María Bastida Bermejo
Publication date: 2024
Published by: Castile and León Society of Hematology and Hemotherapy
Title: Innovative Cellular Therapies for Autoimmune Diseases: Expert-Based Position Statement and Clinical Practice Recommendations from the EBMT Practice Harmonization and Guidelines Committee
IBSAL Authors: Fermin Sanchez-Guijo
Publication date: February 9, 2024
Journal: eClinicalMedicine
Title: Data-Driven, Harmonized Classification System for Myelodysplastic Syndromes: A Consensus Paper from the International Consortium for Myelodysplastic Syndromes
IBSAL Authors: Maria Diez Campelo, Alberto Orfao
Publication date: October 8, 2024
Journal: The Lancet Haematology
Title: Position Statement on Cardiac Computed Tomography Following Left Atrial Appendage Occlusion
IBSAL Authors: Ignacio Cruz González
Publication date: August 12, 2024
Journal: JACC: Cardiovascular Interventions
Title: Clinical Practice Guideline on the Management of Vestibular Schwannoma
IBSAL Authors: Ángel Batuecas Caletrio, Santiago Santa Cruz Ruiz
Publication date: February 2024
Journal: Acta Otorrinolaringológica Española
Title: Myofunctional Therapy (Oropharyngeal Exercises) for Obstructive Sleep Apnea
IBSAL Authors: Inés Llamas Ramos
Publication date: April 5, 2024
Published by: Ministry of Health. Canary Islands Health Service
Title: Guidelines for Discharge Recommendations for Adult Patients Who Have Received a Hematopoietic Stem Cell Transplant
IBSAL Authors: Lucía López Corral
Publication date: March 5, 2024
Published by: Spanish Group for Hematopoietic Transplants and Cell Therapy
Title: Effectiveness, Safety, and Cost-Effectiveness of Automated Systems for Detecting Adverse Drug Reactions
IBSAL Authors: Cristina Lugones Sánchez
Publication date: June 27, 2024
Published by: Ministry of Health. Canary Islands Health Service
Title: Consensus Guidelines and Recommendations for the Management and Response Assessment of Chimeric Antigen Receptor T-Cell Therapy in Clinical Practice for Relapsed and Refractory Multiple Myeloma: A Report from the International Myeloma Working Group Immunotherapy Committee
IBSAL Authors: María Victoria Mateos Manteca
Publication date: August 2024
Journal: The Lancet Oncology
Title: Position Paper by the Spanish Working Group on Crohn’s Disease and Ulcerative Colitis (GETECCU) on Cardiovascular Disease in Patients with Inflammatory Bowel Disease
IBSAL Authors: Fernando Muñoz
Publication date: November 28, 2024
Journal: Gastroenterology and Hepatology
Title: Current Trends in the Treatment of Malignant Pleural Effusion: Evidence, Guidelines, and Best Practice Recommendations
IBSAL Authors: Rosa Cordovilla
Publication date: December 17, 2024
Journal: JCO Oncology Practice
Title: SEOM 2023 Clinical Guidelines
IBSAL Authors: César Rodríguez
Publication date: September 26, 2024
Journal: Clinical and Translational Oncology
Title: Multidisciplinary Approach for Locally Advanced Non-Small Cell Lung Cancer (NSCLC): 2023 Expert Consensus of the Spanish Lung Cancer Group (GECP)
IBSAL Authors: Jose Luis González Larriba, Edel Del Barco Morillo, Joaquin Casal Rubio, Rosario Garcia Campelo, Rafael López Castro, Mariano Provencio
Publication date: March 26, 2024
Journal: Clinical and Translational Oncology
Title: Recommendations for the Safe Use of High-Risk Medications in Pediatrics
IBSAL Authors: María José Otero
Publication date: December 2024
Published by: Ministry of Health, Institute for the Safe Use of Medicines
Title: Recommendations and Minimum Compatibility Requirements for the Search for Unrelated Donors for Hematopoietic Stem Cell Transplants
IBSAL Authors: Estefanía Pérez López
Publication date: November 2024
Published by: Ministry of Health. National Transplant Organization
Title: International Myeloma Working Group Immunotherapy Committee Consensus Guidelines and Recommendations for the Optimal Use of T-Cell-Engaging Bispecific Antibodies in Multiple Myeloma
IBSAL Authors: Maria Victoria Mateos, Noemi Puig
Publication date: May 2024
Journal: The Lancet Oncology
Title: Therapeutic Drug Monitoring in Inflammatory Bowel Diseases. Position Statement of the Spanish Working Group on Crohn’s Disease and Ulcerative Colitis
IBSAL Authors: Fernando Muñoz Núñez, José Germán Sánchez-Hernández
Publication date: May 2024
Journal: Gastroenterology and Hepatology
Title: SEOM-GEMCAD-TTD Clinical Guideline for the Diagnosis and Treatment of Gastric Cancer (2023)
IBSAL Authors: Fernando Rivera, Javier Gallego
Publication date: July 18, 2024
Journal: Clinical and Translational Oncology
Title: Clinical Protocol for the Use of Brexucabtagene Autoleucel in the Treatment of Patients with Refractory or Relapsed Mantle Cell Lymphoma After Two or More Lines of Systemic Therapy in the National Health System
IBSAL Authors: Fermín Sánchez-Guijo Martín
Publication date: January 22, 2024
Published by: Deputy Directorate General of Pharmacy. Directorate General of the National Health System’s Common Portfolio of Services and Pharmacy. Ministry of Health
Title: Disconnecting the Monitor for a Person with Kidney Disease Who Has an Arteriovenous Fistula
IBSAL Authors: Mª Luz Sánchez Tocino
Publication date: January 30, 2024
Published by: Spanish Society of Nephrology Nursing (SEDEN)
Title: Diagnostic Requirements: Assessment of Vascular Access Recirculation
IBSAL Authors: Mª Luz Sánchez Tocino
Publication date: January 30, 2024
Published by: Spanish Society of Nephrology Nursing (SEDEN)
Title: An Update on Vasculitis. Clinical Guidelines from the Castile and León Society of Angiology and Vascular Surgery
IBSAL Authors: Oliver Bonnelly, José Ángel Torres Hernández, Sergio Valverde García, P. Velasco
Publication date: June 20, 2024
Published by: Castile and León Society of Angiology and Vascular Surgery
Title: Harmonization of Diagnostic Criteria for Mastocytosis for Use in Clinical Practice: WHO vs. ICC vs. AIM/ECNM
IBSAL Authors: Alberto Orfao
Publication date: December 2024
Journal: The Journal of Allergy and Clinical Immunology
Title: Guide to the Diagnosis and Treatment of Spinal Cord Disorders
IBSAL Authors: Lourdes Vázquez López
Publication date: 2024
Published by: Spanish Group for Hematopoietic Transplantation and Cell Therapy (GETH)
Title: Aneurysms of the Upper Extremity
IBSAL Authors: Sergio Valverde García, José Antonio Carnicero Martínez, P. Velasco, J. Flórez
Publication date: June 20, 2024
Published by: Castile and León Society of Angiology and Vascular Surgery
Title: Functional Proteomics Based on Protein Microarray Technology for Biomedical Research
IBSAL Authors: Pablo Juanes-Velasco, Carlota Arias-Hidalgo, Alicia Landeira-Viñuela, Ana Nuño-Soriano,
Rafa Góngora, Ángela-Patricia Hernández, Manuel Fuentes
Publication date: January 14, 2024
Journal: Advances in Protein Chemistry and Structural Biology