{"id":24369,"date":"2026-03-05T09:00:00","date_gmt":"2026-03-05T07:00:00","guid":{"rendered":"https:\/\/ibsal.es\/ricapps-is-spearheading-the-pandora-study-to-prevent-anxiety-and-depression-using-an-app\/"},"modified":"2026-08-04T12:54:13","modified_gmt":"2026-08-04T10:54:13","slug":"ricapps-is-spearheading-the-pandora-study-to-prevent-anxiety-and-depression-using-an-app","status":"publish","type":"post","link":"https:\/\/ibsal.es\/en\/ricapps-is-spearheading-the-pandora-study-to-prevent-anxiety-and-depression-using-an-app\/","title":{"rendered":"RICAPPS is spearheading the PANDORA study to prevent anxiety and depression using an app."},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>In Spain, about 2.5 million people suffer from depression and another 2 million from anxiety.<\/strong><\/p>\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p class=\"wp-block-paragraph\"><strong>There are effective treatments available for established depression and anxiety, but to prevent new cases from developing, prevention is the best option.<\/strong><\/p>\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p class=\"wp-block-paragraph\">The Research Network on Chronicity, Primary Care, and Health Promotion and Prevention (RICAPPS), through its <strong>Mental Health, Services, and Primary Care group (SAMSERAP) of the<\/strong> Biomedical Research Institute of Malaga and the Nanomedicine Platform, IBIMA BIONAND Platform, and the Biomedical Research Institute of Salamanca (IBSAL) <strong>, is launching a preventive intervention (PANDORA<\/strong> : <em><strong>Prevention<\/strong> of <strong>Anxiety<\/strong> and <strong>Depression<\/strong> <strong>Over<\/strong> <strong>Risk<\/strong> <strong>Assessment<\/strong> : a randomized controlled trial<\/em> ) <strong>for anxiety and depression<\/strong> <strong>, implemented via a mobile <em>app<\/em> .<\/strong> To this end, 2,600 people aged 18 to 65 without significant depression or anxiety will be recruited in Spain and Chile. <\/p>\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p class=\"wp-block-paragraph\">According to Juan Bell\u00f3n, the project\u2019s principal investigator, \u201cwe will assess whether a personalized digital intervention delivered via mobile phone can reduce new cases of common mental disorders and their significant social and economic impact; and the fact is that we know <strong>treatments only reduce the disease burden ( <\/strong>years lived with a poor quality of life) <strong>of depression and anxiety<\/strong> <strong>by between 30% and 50% <\/strong>, respectively. This is partly because, of the total number of depression and anxiety cases in a given year, more than 40% are new cases, and treatments do little or nothing to prevent these new cases from occurring.\u201d   <strong>&#8220;To that end, prevention is the answer. We now know that preventive psychological and psychoeducational interventions, along with physical exercise, prevent between 20% and 40% of new cases of depression and anxiety from developing.&#8221; <\/strong><\/p>\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p class=\"wp-block-paragraph\">In fact, <strong>today more than 90% of adults own a cell phone and use it to access the internet. Therefore <\/strong>, it is highly likely that <strong>the PANDORA initiative could reach many millions of people in Spain and South America.<\/strong><\/p>\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<h4 class=\"wp-block-heading\">Depression and Anxiety in Spain<\/h4>\n\n<p class=\"wp-block-paragraph\">Depression and anxiety are the most common mental illnesses.  <strong>In Spain, about 2.5 million people suffer from depression and another 2 million from anxiety.<\/strong>  In 2021, depression and anxiety\u2014among all physical and mental illnesses\u2014ranked second and eighth worldwide in terms of years lived with a poor quality of life, and it is estimated that by 2030, depression will rank first.  <strong>Recurring thoughts of not wanting to live are common among people with depression, and nearly one million people worldwide take their own lives each year.<\/strong><\/p>\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p class=\"wp-block-paragraph\">But their impact goes beyond health. Depression and anxiety are more common among working-age adults and are among the conditions that result in the most sick leave, which tends to be very prolonged. People with depression and anxiety perform less effectively at work and face significant difficulties finding or keeping a job. As a result, <strong>depression and anxiety cost Spain 12,000 million euros annually.<\/strong>   <\/p>\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<h4 class=\"wp-block-heading\">The PANDORA Project<\/h4>\n\n<p class=\"wp-block-paragraph\">Participation in the PANDORA study is currently open to any citizen of Spain or Chile. To participate in the PANDORA study, visit the study\u2019s official website at <a href=\"https:\/\/pandorasalud.org\/\">https:\/\/pandorasalud.org\/<\/a> <\/p>\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p class=\"wp-block-paragraph\">The study will follow all participants for one year, monitoring the incidence of new cases of depression and anxiety. <strong>Participants will be randomly assigned to three groups<\/strong>: two intervention groups and one control group, to evaluate the PANDORA intervention.<\/p>\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p class=\"wp-block-paragraph\"><strong>The PANDORA intervention will be delivered through an app<\/strong> (available for Android and iOS) and includes tips and exercises from <strong>four intervention groups<\/strong> that have been scientifically proven to be effective in preventing anxiety and depression: <strong>\u201cget more active,\u201d \u201csleep better,\u201d \u201cimprove relationships,\u201d and \u201cimprove emotional well-being.\u201d<\/strong> It will also include calculators to predict the risk of developing depression and anxiety over the next 12 months. Assessments of depression and anxiety prevention will be conducted monthly, as well as at 6 and 12 months. <\/p>\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p class=\"wp-block-paragraph\">The app will also identify the risk factors for depression and anxiety present in each person, highlighting those that could be addressed for prevention, and <strong>will automatically and personally recommend the <\/strong> <em>app<\/em> <strong>content<\/strong> <strong>that would be most useful to the<\/strong> <strong>user <\/strong>in their specific situation.<\/p>\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p class=\"wp-block-paragraph\"><strong>Users implement this plan based on their motivation and availability,<\/strong> and the PANDORA <em>app<\/em> tracks and reports on their progress and suggests new actions when the risk of depression and anxiety increases. The app also allows users to filter its content by topic, priority within the personalized prevention plan, duration in minutes (from 2 to 10 minutes), and format (text, videos, \u201ctrivia,\u201d exercise, etc.). <\/p>\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<p class=\"wp-block-paragraph\">\u201cThere are two versions of PANDORA,\u201d explains Juan Bell\u00f3n, a researcher at RICAPP and the project coordinator; both have the same content but are organized differently. \u201cIn addition, some users may also be randomly assigned <strong>to the comparison group.<\/strong> This group of people <strong>is very important and essential for determining with certainty whether the PANDORA intervention prevents depression and anxiety compared to the comparison group.\u201d<\/strong> <\/p>\n","protected":false},"excerpt":{"rendered":"<p>In Spain, about 2.5 million people suffer from depression and another 2 million from anxiety. There are effective treatments available for established depression and anxiety, but to prevent new cases [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":24370,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"footnotes":"","_members_access_role":[],"_members_access_error":""},"categories":[238,239],"tags":[245],"class_list":["post-24369","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-news-highlights","tag-mental-health"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.12 (Yoast SEO v28.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>RICAPPS is spearheading the PANDORA study to prevent anxiety and depression using an app. | IBSAL<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibsal.es\/en\/ricapps-is-spearheading-the-pandora-study-to-prevent-anxiety-and-depression-using-an-app\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"RICAPPS is spearheading the PANDORA study to prevent anxiety and depression using an app.\" \/>\n<meta property=\"og:description\" content=\"In Spain, about 2.5 million people suffer from depression and another 2 million from anxiety. 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