Team leader

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    • IIMD18
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    Felipe X. Pimentel Muiños

    Consejo Superior de Investigaciones Científicas

Research team:
  • José Luis Cedillo Mireles
  • Álvaro Fernández Cabrera
  • Rachid Taouil Hammouti
Research associates:
  • Inmaculada Serramito Gómez
  • Raquel Villamuera del Sordo

Research focus

  • Understanding the molecular mechanisms in autophagy signal transduction by ATG16L1 and their possible role in Chron’s disease.
  • Study of the physiological role of a new protein motif identified in the transmembrane molecule TMEM59 and its relationship with autophagy, innate immunity against infectious agents and inflammation.
  • Role of autophagy induced by members of the Bcl2 family in apoptosis.
  • Identification of apoptotic mechanisms in the liberation of cytochrome c from the mitochondria in absence of the conventional Bak/Bax-dependent pathway.
  • Functional characterization of a collection of molecules capable of inducing atypical cell death.


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